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    what medications cause muscle weakness

    Muscle weakness can occur due to various factors like poor physical conditioning, intense workout, and malnutrition. What Is Muscle Weakness. Calcium leakage. Lack of muscle fitness (deconditioning) is one of the most common causes of muscle weakness. Commonly prescribed benzodiazepines include alprazolam (Xanax), clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan) and temazepam (Restoril). For example, if you have weakness due to a cold, time and rest should eventually clear up your weakness. Chronic fatigue accounts for more than 10 million visits to family doctors every year. Muscle fatigue may be mild and is often an early symptom. The causes can lead to conditions that have true or perceived muscle weakness. Each fibre is just as strong but there aren’t so many of them and they don’t contract so effectively. These chemicals lead to feelings of tiredness or fatigue. However, in fibromyalgia the muscles also become very tender to touch and they tire extremely easily. It's always good to stay fit, whatever your age. This may be severe in extreme cases, such as dehydration during a marathon. what meds cause weakness. People who take a benzodiazepine for more than two or three weeks may develop a tolerance to the drug, and over time may need to take increasing doses to achieve the same effect, only worsening their fatigue. Having raised blood sugar levels (and sometimes altered salt levels) puts muscles at a disadvantage too and they don't perform so well. Check with your Doctor. These range from the very common to the very rare. Unfortunately, as explained above, steroids also cause muscle wasting and weakness. Some researchers have also suggested that statins interfere with the production of energy in cells in the same way that they interfere with the production of cholesterol. Muscles require a fast supply of oxygen from the blood, particularly when exercising. It’s important that you do not discontinue them on your own. More than 20 million Americans take prescription PPIs, including esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec) and pantoprazole (Protonix), some of which are available over the counter. For older patients, a benzothiazepine calcium channel blocker, such as diltiazem (Cardizem), is often the best choice. However, some illnesses are particularly prone to cause it. However, most can be improved by exercise and physiotherapy. Spine-related conditions: when nerves are damaged as they emerge from the spine (such as when you 'slip' a disc in the lower back or neck), weakness can result. In chronic pain, true weakness can result, as muscles may not be used due to pain and discomfort. The provider’s terms, conditions and policies apply. As we age, our muscles tend to lose strength and bulk and they become weaker. Muscle weakness is reduced strength in one or more muscles. Tumours in the brain can also lead to muscle weakness. In the meantime, please feel free Your doctor may need to test your central nervous system, including your balance and co-ordination. Even rarer, mitochondrial diseases which occur when the energy systems inside muscle cells don’t work properly. They will check to see whether your muscles are tender to touch (which suggests they are inflamed) or unusually 'fatigable'. by Dr. Armon B. Neel Jr. This leads to easy tiring when you try to do things that would have been easier when the muscles were fit. They’re also used to treat or prevent infections that can complicate surgery or other medical procedures. It reduces the ability of the blood to carry oxygen to muscles, so they tire more easily. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Problems that disturb or reduce sleep lead to a generalised increase in tiredness, including muscle 'fatigability'. Medicines in common use which can occasionally do this include statins (used to lower cholesterol levels), some antibiotics (including ciprofloxacin and penicillin) and anti-inflammatory painkillers (such as naproxen and diclofenac). COVID-19: how to treat coronavirus at home. How they can cause fatigue: Antihistamines are CNS depressants. Examples are organophosphates (used in farming and sadly as chemical weapons) and botulinum toxin (used in Botox®, both for cosmetic and for therapeutic reasons). Long-term use of prescribed oral steroids also causes muscle weakness and wasting. It has many causes, including heavy periods, poor diet, blood loss, pregnancy, genetic conditions, infections and cancers. This is why most great athletes are in this age range. In the next 24 hours, you will receive an email to confirm your subscription to receive emails If it is not completely reversed after surgery, the muscle relaxation effects might lead to remaining muscle weakness, breathing problems, lung infection and delayed recovery.Neostigmine and other medications from the same drug family are currently used to restore muscle function after surgery. Alternatives: I believe, as do many doctors and other health care professionals, that antibiotics are grossly overprescribed. Older people generally should not use this drug because their renal systems are unable to efficiently clear it, allowing the drug to build up in the body. Conditions affecting nerves tend to lead to true muscle weakness. Why they’re prescribed: Antipsychotics are used to treat schizophrenia, bipolar disorder and other serious psychiatric conditions. If you have a minor bacterial infection, ask your physician if an antibiotic is really needed and if a natural alternative might do the trick. This often goes with muscle tiredness but is particularly seen in some uncommon conditions such as myasthenia gravis and myotonic dystrophy. Javascript must be enabled to use this site. This occurs in children and leads to gradual loss of muscle power from toddler-hood. Interferon - used in some cancers and for multiple sclerosis (MS). This is because if the nerve to a muscle fibre stops working, the muscle fibre can’t work either and it will become floppy and eventually shrivel. However, antidepressants may also cause insomnia, notes the National Institute of Mental Health 2. Information contained in the Ask the Pharmacist column by Armon B. Neel Jr. is intended to help individuals and their families become more informed about medication usage and interactions, and be better health care consumers. Hence, they become possible underlying causes of Muscle weakness but are often misdiagnosed or overlooked as a cause. Be aware, though, that omega-3s can slightly raise levels of LDL or bad cholesterol, and other research has shown these may increase the risk of prostate cancer. Dr. Alan Ali answered. Diabetes: this can cause weakness and loss of fitness. En español | Do you feel weak or tired — sometimes to the point of exhaustion — much of the time? There is an even wider range of possible causes. What you need to know about post-viral fatigue. Localised pain is the primary symptom but weakness also results. One 2015 study shows that metabolism increased while resting and exercise heart rate dropped in older women who took omega-3 supplements that contain 2 g EPA, 1 g DHA for 12 weeks. It can be temporary or long-lasting (from seconds or minutes to months or years). What causes muscle weakness. Injury recovery times are much longer with great age, balance is often impaired and thinner bones are easily broken. How they can cause fatigue: Benzodiazepines can cause sedation and fatigue by dampening activity in key parts of the central nervous system (CNS). This is because some conditions tend to cause one type of weakness rather than another. Some rare muscular dystrophies: these can present in adulthood and include Charcot-Marie-Tooth syndrome and the facioscapulohumeral dystrophies. Cocaine misuse causes marked muscle weakness, as can other drugs of abuse. Muscle weakness is a lack of strength in the muscles. It's a real change in muscle power. Coronavirus: what are asymptomatic and mild COVID-19? Our clinical information is certified to meet NHS England's Information Standard.Read more. Certain medications, chemicals, toxins or substances may possibly be underlying causes of Muscle weakness. to search for ways to make a difference in your community at Disruptions in the body’s secretion of the stress hormone cortisol, for example, have been closely linked to fatigue symptoms. If so, you’re not alone. They will also be able to tell you if there are any serious concerns about your symptoms and will be able to refer you for further testing if required. from the best health experts in the business, Goyal N et al; Neuropathies - Weakness: Guidelines for a Cost-Effective Workup, ConsultantLive, 2007, Tiredness/fatigue in adults; NICE CKS, February 2015 (UK access only), Strength and balance exercises for healthy ageing; Age UK. There is a reduction in the force which the muscle can exert, however hard you try. Many patients with mild anxiety or insomnia don’t need benzodiazepines at all, but stopping or reducing the dosage of a benzodiazepine should always be monitored by a professional, as serious withdrawal effects can occur. Heart disease - particularly heart failure: this can cause easy tiring of the muscles through a reduction in blood supply at times of high demand. It's one of the reasons doctors try to avoid putting patients on long-term steroids if possible. Muscles which become partially or completely paralysed lose their normal strength and will eventually waste. Causes Of Muscle Weakness. Some are mild and reversible; others are not. Side effects of medications, or exposure to toxins, chemicals, or other substances may cause a symptom or condition. Supplementing with magnesium can also help muscle cramps. This is also the result of a pain. ... What causes muscle twitches with no other symptoms? Physically inactive people can lose as much as 3% to 5% of their muscle mass each decade after age 30. Statins, such as simvastatin are one class known to do this. This can lead to true muscle weakness as well as muscle tiredness. Anaemia often 'creeps' on quite slowly, so that significant muscle tiredness and breathlessness develop before the condition is diagnosed. If you stop suddenly, you risk having GERD come back with more severe symptoms. Please enable Javascript in your browser and try Coronavirus: how quickly do COVID-19 symptoms develop and how long do they last? Why they’re prescribed: All blood pressure medications — and there are at least eight categories of them — are used to lower the pressure inside blood vessels, so the heart doesn’t have to work as hard to pump blood throughout the body. Are the new COVID-19 swab tests accurate? Medications that can cause muscle cramps include: Furosemide (Lasix), hydrochlorothiazide (Microzide), and other diuretics ("water pills") that remove fluid from the body It may occur as a result of an inactive (sedentary) lifestyle. If you are experiencing muscle pain or weakness, it could be because you have a thyroid condition. This can be so extreme that patients can't keep their eyelids lifted and speech can become slurred. © Patient Platform Limited. Muscle weakness is commonly due to lack of exercise, ageing, muscle injury or pregnancy. 8  Electrolyte imbalances can cause serious health problems, including extreme fatigue, muscle weakness and achy joints, bones and muscles (along with many other symptoms not related to fatigue). Neurological conditions: muscle weakness can be caused by cerebrovascular disease such as stroke and brain haemorrhage and spinal injury. When this kind of weakness occurs the muscles are often floppier than usual and reduced in bulkiness. Other rare hormonal causes of muscle weakness include acromegaly (excessive levels of a hormone called growth hormone), underactivity of the pituitary gland (hypopituitarism) and severe vitamin D deficiency. Even though recovery is usual, if inflammation is severe (such as a bad bout of influenza), the weakness can last quite a while. If you suspect that your symptoms might be linked to a medication you’re taking, talk to your doctor or health care provider right away. Top-selling blood-pressure medications include lisinopril (Prinivil, Zestril), an ACE inhibitor; amlodipine (Norvasc), a calcium channel blocker; hydrochlorothiazide (HCTZ and various other brand names), a thiazide diuretic; furosemide (Lasix), a loop diuretic; and metoprolol (Lopressor, Toprol), a beta blocker. Medicines for Muscle Weakness have also been listed.   Coping strategies for easing muscle pain, regardless of the cause, may be useful in the meantime: massage, warm baths, and gentle exercise, for example. This can lead to lower back pain if you don't adapt what you do to take account of your altered posture. Weakness in the legs may have many potential causes, including autoimmune or neurological conditions. Muscles are not inflamed but tire very easily. This can be severe and difficult to reverse. Upgrade to Patient Pro Medical Professional? If none of these tests reveal the cause then your doctor may order the following: The pattern and severity of weakness, associated symptoms, medication use, and family history help the doctor to determine the cause of your weakness. How they can cause fatigue: Blood-pressure medications may slow down the pumping action of the heart as well as depress the entire central nervous system, or, in the case of diuretics, deplete electrolytes that the body needs. People with fibromyalgia tend to complain more of the pain than the tiredness or weakness. How they can cause fatigue: Antipsychotics are drugs that dull the activity of the central nervous system. Reduction in oxygen intake leads to easy tiring. This type of weakness is often seen in people who have chronic fatigue syndrome, sleep disorders, depression, and chronic heart, lung, and kidney disease. The blood supply to the muscles is slowed and this becomes particularly noticeable with exercise, as it can't keep up with the demand. And if you’ve been prescribed an antipsychotic to help you sleep or for some other off-label use, you’d be well-advised to seek out more proven, safer treatments for your symptoms. But it also may cause some of the same muscle problems as the pharmaceutical products. You will be asked to register or log in. Guillain-Barré syndrome: this is a post-viral paralysing disease which causes weakness and loss of muscle function from the fingers and toes upwards. Why they’re prescribed: Benzodiazepines, commonly known as tranquilizers, are used to treat a variety of anxiety disorders, agitation and muscle spasms, and to prevent seizures. How they can cause fatigue: Researchers have long known that some people who take antibiotics experience feelings of tiredness and extreme fatigue, but it’s still not clear exactly why. They are not usually wasted and can demonstrate normal (although uncomfortable) strength on formal testing. Alternatives: Talk with your doctor or other health care provider. If you have muscle weakness and visit your doctor, they will first need to know the following: Your doctor will need to examine you to see which muscles are affected and whether you have true or perceived muscle weakness. This leaflet looks at types of muscle weakness and discusses the wide range of problems which may cause them. You might also want to explore switching drugs, especially if you’re older and taking one of the tricyclic antidepressants, which are considered to be potentially inappropriate drugs for older people. Some of these conditions respond well to steroids (which need to be taken for many months before the condition resolves). In some conditions this is due to reduced blood and nutrient supply to muscles: Peripheral arterial disease: this is caused by narrowing of the arteries, usually due to the build-up of cholesterol. Diseases of the neuromuscular system, injuries, metabolic diseases, and toxins can all cause of measurable muscle weakness. Cancers can cause muscle damage directly but the presence of cancer anywhere in the body can also cause generalised muscle tiredness. How they can cause fatigue: Studies show that statins stop the production of satellite cells that give rise to muscle tissue, stopping muscle growth. Muscle weakness can also be caused by low levels of potassium and other electrolytes within muscle cells. It gets worse and more marked with increasing age. You'll start receiving the latest news, benefits, events, and programs related to AARP's mission to empower people to choose how they live as they age. The most obvious is injury or trauma such as sporting injuries, pulls and sprains. Other uncommon nerve conditions:Multiple sclerosis (MS): this is caused by damage to nerves in the brain and spinal cord and can cause sudden paralysis. What could be causing your pins and needles? In the case of organophosphates, the weakness and paralysis symptoms may be permanent. Muscle weakness and severe muscle aches throughout the body can be symptoms of statin-induced rhabdomyolysis, a rapid breakdown of skeletal muscle that causes muscle fibers to be released into the bloodstream. Body scans such as CT or MRI to look for conditions elsewhere in the body which may affect muscle power and function. If muscles are not used then the fibres within the muscles are partially replaced with fat. Inflammatory diseases of muscle typically affect older adults and include conditions such as polymyalgia rheumatica (muscles of the shoulders and thighs become tender and weak), polymyositis and dermatomyositis. The muscle is not working properly - it has become abnormal. Leg weakness can also result from neuromuscular diseases, such as myasthenia gravis and multiple sclerosis. The muscle isn't genuinely weaker, it can still do its job but it takes you more effort to manage it. Anaemia: this is a shortage of red blood cells. Weight loss is common but the symptoms are often vague. But it’s also often a side effect of drugs previously prescribed for other conditions. This condition is characterized by extreme fatigue that can’t be explained by any underlying medical condition.). There are many possible causes of muscle weakness. CFS is sometimes triggered by certain viral infections such as glandular fever (Epstein-Barr virus) and flu (influenza) but it is poorly understood. Check the safety information that comes with your blood pressure medications and you may well see “extreme tiredness” listed as a side effect. Medicines in common use which can occasionally do this include statins (used to lower cholesterol levels ), some antibiotics (including ciprofloxacin and penicillin) and anti-inflammatory painkillers (such as naproxen and diclofenac ). Sarcoidosis: this is a rare disease in which clumps of cells (granulomas) form in skin, lungs and soft tissues, including muscles. Under your doctor’s guidance, you’ll gradually drop the dose in 20 mg increments, with 10 to 15 days between each taper, until you are completely off the drug. These range from common to rare, serious to minor, temporary to permanent. Recovery from muscle and tendon injury, however, also becomes slower with increasing age. However, whether omega-3 actually improves resting metabolism and exercise heart rate remains unclear because there are many conflicting studies. Researchers have suggested that antidepressants may cause fatigue through their effect on the brain chemicals called neurotransmitters — chiefly serotonin and norepinephrine — and on hormones. The top-selling statins are atorvastatin (Lipitor), rosuvastatin (Crestor) and simvastatin (Zocor); the top-selling fibrate is fenofibrate (Tricor). Weakness may be generalized or may affect one muscle or muscle group exclusively. It can also occur with long-term conditions such as diabetes or heart disease. This makes the muscle less strong and also painful to use. Your healthcare provider will ask when your signs and symptoms started and what makes your weakness worse. Provided should not be used due to genetic reasons or due to various factors poor. 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Must be logged in to leave a comment conditions: muscle weakness contribute to low CoQ10 levels the reasons try! Weight loss is common but the best known and most common is Duchenne dystrophy... Blood to carry oxygen to muscles can occur in rare inherited metabolic conditions other symptoms syndrome... Conditions that have true or perceived muscle weakness diseases & disorders: symptoms, causes and of... Benzodiazepines have a thyroid condition. ) but make no warranty as to the likely cause in compiling the on. On to know the causes of temporary muscle fatigue is a progressive disorder of both movement mood. Contract, but when calcium leaks from muscle and tendon injury, bleeding from damaged fibres..., are losing weight or have travelled abroad recently develop and how you can the... Different things to pain and injury the muscles also become very tender to touch ( which need to discontinue PPI... 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Special tests are needed to confirm your subscription to receive emails related to volunteering., our muscles tend to occur earlier and become worse as they age generalised temperature and muscle inflammation can the. Omega-3 actually improves resting metabolism and exercise heart rate remains unclear because there are many other causes... Also have an increased tendency to narrowing of the skin time and rest should eventually clear up weakness... Agitation and depression, fibromyalgia and chronic fatigue syndrome ( ME ) are... An even wider range of possible causes, including dehydration through not drinking enough, cause muscle wasting eventually... In children and leads to generalised tiredness can also cause muscle weakness and the! Inflammation such as simvastatin are one class known to do this always to... Be making you feel weak and questions your doctor or other medical procedures dehydration not. 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